Defining the best crystalline form of an API is crucial in drug development, since it has a significant impact on the effectiveness of the formulation and, therefore, the bioavailability of the finished dosage form. CARBOGEN AMCIS has established a capability that supports our customers with crystallization investigations, including solubility tests, salt screening, and optimization of the crystallization process and the solid-liquid separation in the API isolation process. Polymorphism screening complements the service portfolio.
We offer online monitoring of critical parameters such as particle size, turbidity, temperature, and pH value. We also provide analytical services, dedicated to solid phase characterization; including hot-stage microscopy, differential scanning calorimetry and X-ray powder diffraction.
CARBOGEN AMCIS is a leading service provider, offering a portfolio of drug development and commercialization services to the pharmaceutical and biopharmaceutical industries at all stages of drug development. Our integrated services for Drug Substances (DS) and Drug Products (DP) provide innovative solutions to support timely and safe drug development.